What is mescaline ?
What is mescaline?
3, 4, 5-trimethoxy phenethyl amine is known
as mescaline. Mescaline is a naturally occurring psychedelic alkaloid
of the phenethyl amine class, known for its hallucinogenic effects.
Mescaline occurs naturally
mescal buttons. The routine test shows that mescaline contains a primary aliphaticamino group and three methoxyl groups.
On oxidation with alkaline
permanganate, mescaline gives 3, 4, 5-trimethoxy benzoic acid
and thus the probable structure of mescaline is (I).
 |
| ( I ) |
This has been confirmed by synthesis. There
are several methods for the synthesis of mescaline. The
synthesis of mescaline from 3, 4, 5-trimethoxy benzoic acid is an
important method.
In this method, 3,4,5-trimethoxy benzoic
acid reacts with PCl5 to form , 3,4,5-trimethoxy benzoyl chloride, which on rosenmund reduction gives
3,4,5-trimethoxy benzaldehyde.
Further 3,4,5-trimethoxy
benzaldehyde reacts with alkaline nitro methane forms
3,4,5-trimethoxy omga-nitro styrene followed reduction resulting in
the formation of mescaline.
The other methods for the preparation
of mescaline are also shown below.
Use of mescaline
Mescaline is one type pressor drug
which is used to increase the blood pressure in human body .Sample of the mescaline
powder is shown below.
Summary
- What is mescaline in chemistry ?
- What is the important use of mescaline?
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